This section summarises the auto flammability values from all registered dossiers for the substance. This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. This section displays the values related to repeated dose toxicity from all registered dossiers for the substance. If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C). ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information. More detailed information is available in the dossiers. pH provides substance information on the substance’s acidity level measured in pH at a temperature measured in °C and a concentration measured in (milli)grams per litre. A substance may have more than one CAS number associated. More information about the EC Inventory can be found here. This section summarises the Ecotoxicological information provided from all registered dossiers for the substance. Degradation rate constant (Ozone) provides substance information on the substance’s degradation rate constant with Ozone as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. This section searches three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). If only waived data is available for the substance, following justifications for data-waiving can be displayed in the Brief Profile: Some endpoints are not included in the Brief Profile due to the use of free text and/or complex field(s) in the reporting of information, which cannot be easily summarised by an automatic algorithm. The brief profile is based on non-confidential data contained in ECHA’s databases at the time of generation. LC50 for marine water fish provides substance information on the substance’s lethal concentration for 50% of the marine water fish in the test, displayed in milligram per litre. Registrant can provide information on eye exposure by selecting one of the following hazard assessment conclusions: Data for general population – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for the general population). Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). ECHA has no public registered data indicating whether or in which chemical products the substance might be used. Do not induce vomiting. Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. This section provides an overview of the type of study records behind the presented results and data waving justifications. Immediately call a poison center or doctor/physician. The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Oxidation reduction potential in mV at 20°C provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature of 20°C. Registrants can choose from the following picklist endpoint conclusions/effect levels: Eye irritation provides substance information on the substance’s irritation effect on the eye. 25,26 It is used in the production of commercial polyesters and polyamides. EC10 / LC10 or NOEC for microorganisms provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested microorganisms or the no observed effect concentration for microorganisms. This section summarises the values related to long term toxicity to aquatic invertebrates from all registered dossiers for the substance. 145 for adipic acid. The Candidate List includes substances that are subject to additional protocols and reporting obligations and which may eventually be included in the Authorisation list, further limiting their use. It is an alpha,omega-dicarboxylic acid which has simple 5 carbon linear dicarboxylic acid (HO 2 C−R−CO 2 H). If swallowed: rinse mouth. REACH registration dossiers notifications. This section summarises the values related to toxicity to microorganisms from all registered dossiers for the substance. More important for COO: enter a "0" if only two numbers are By employing reliable structural data on malonic, succinic, glutaric, adipic and pimelic acids, obtained by a single crystal X-ray crystallographic study of these systems (using a CCD detector), the total electron densities and the Laplacians at the critical points of various bonds including the dimeric hydrogen bonds have been obtained. Only non-confidential use descriptors are displayed and for readability purpose only use descriptors occurring in more than 5% of the total occurrences are displayed. Although the related "linear" dicarboxylic acids adipic and succinic acids are water-soluble only to a few percent at room temperature, the water-solubility of glutaric acid is over 50% (w/w). Data is generally displayed in milligram per kilo bodyweight. Within each of these categories, data is prioritised further by duration (in hours), with longer prioritised over shorter. Rinse skin with water or shower. This main layer contains sublayers for the chemical formula, atom connections and hydrogen atoms. Registrant can provide information on the long and acute/short term exposure for both systemic and local effects of inhalation exposure of workers and/or general population by selecting one of the following hazard assessment conclusions: Prioritisation of display occurs based on the order above. If so, the data provided is not processed for the Brief Profile. Xingxiang Zhang, in Smart Fibres, Fabrics and Clothing, 2001. The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. Dissipation Half-life of parent compound provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year. This section displays the values related to reproductive toxicity from all registered dossiers for the substance. Please see the registered dossiers for substance information for the following endpoints: The ’Substance identity’ section links substance identification information from all databases that are maintained by ECHA. Atr.no/Packing Stock Price Number; Glutaric acid monomethyl ester chloride-G104122-10g In most cases, impurities constitute less than 10% of the substance. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Precautions for using this substance have been recommended by its registrants under REACH, as follows: When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier. Registrants can register their substance flammability as: Note: Registrants can also select ‘other’ as the flammability value for their substance. Data is generally displayed in milligrams per kilogram bodyweight per day.Prioritization by test species: See ‘Summary effect on fertility oral route’. This section displays the values related to acute toxicity from all registered dossiers for the substance. Values are generally displayed in milligram per kilo soil (dry weight). Solubility in mg/100g standard fat at 20°C provides substance information on the substance solubility in standard fat in milligram per 100 gram at a temperature of 20°C. All the source data on which the summaries on this page are based, is provided by industry and stored in the ECHA databases. It has a role as a human metabolite and a Daphnia magna metabolite. The BPR regulatory processes identified for the Brief Profile are: Prior Informed Consent (PIC)The PIC Regulation (649/2012) entered into force on 4 July 2014. Bioaccumulation factor (aquatic species) provides substance information on the substance’s bioaccumulative properties not taking account the dimensions. If a substance is classified under multiple CLHs, a link to the C&L Inventory is provided to allow users to view CLH information manually, instead of having the information automatically generated in the Brief Profile. ThOD provides substance information on the substance’s ThOD values displayed in O2 (milli)gram per gram test material. Data generally displayed in milligrams per kilogram bodyweight per day. Hazard for predators provides information on the substance’s hazard assessment conclusion related to predators/secondary poisoning. Each InChI string starts with the InChI version number followed by the main layer. Registrants can register their substance’s bioaccumulation properties as: Registrants can register their substance’s oral/dermal/inhalation absorption rate values in percentages. Registrants can choose from the following picklist endpoint conclusions: Inhalation route provides substance information on the substance’s acute toxicity via the inhalation route. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. The density of glutaric acid is 1.429 g/cm 3 at 15 °C. Oral route provides substance information on the substance’s acute toxicity via the oral route. Registrants can choose from the following (picklist) conclusions: Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above. CAS 110-94-1, EC Number 203-817-2, chemical formula HOOC(CH₂)₃COOH. Derived No- or Minimal Effect Level (DN(M)EL), Toxicokinetics, metabolism, and distribution, Endocrine disrupter mammalian screening - in vivo. Labelling ( CLH ) glutaric acid density REACH registrations and CLP notifications agreement between companies differently... Clp notifiers may classify a substance differently based on count of values provided in % ) species... Boiling point values from all registered dossiers for the substance in REACH registration dossier person fresh... °C at a temperature measured in ( nano/ micro/milli ) molar per litre ‘ BMC ’, dose. 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